The editors of Mast Cell Biology, Drs. Gilfillan and Metcalfe, have enlisted an outstanding group of investigators to discuss the emerging concepts in mast cell biology with respect to development of these cells, their homeostasis, their activation, as well as their roles in maintaining health on the one hand and on the other, their participation in disease.
Extensively illustrated and liberally laced with clinically helpful tools, Clinical Adult Neurology is an affordable reference for all clinicians and residents. With emphasis on diagnostic tools and strategies as well as management pearls and perils, Clinical Adult Neurology will meet the needs of all health care practitioners caring for patients with neurologic disorders. The book is organized into three sections, with Section 1 covering all aspects of neurologic evaluation, Section 2 describing common clinical problems in neurology, and Section 3 discussing all aspects of neurologic diseases. All sections and chapters emphasize the clinical approach to the patient with consistently useful pedagogical tools, including Features tables for diagnostic help with all neurologic diseases, Pearls and Perils boxes that represent pithy distillations of clinical wisdom from leading experts, Key Clinical Questions boxes that help clinicians frame patient diagnosis and management; and annotated bibliographies that highlight the most important references for further study. The book s organization, format, and features all stress the efficient and well-rationed use of medical care for patients with neurologic disease. Succinct content presentations make all information easy to locate and digest. The format will also be a helpful tool for those preparing for examinations.
In the fall of 1980, Genentech, Inc., a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading, at that point the largest gain in stock market history. Coming at a time of economic recession and declining technological competitiveness in the United States, the event provoked banner headlines and ignited a period of speculative frenzy over biotechnology as a revolutionary means for creating new and better kinds of pharmaceuticals, untold profit, and a possible solution to national economic malaise. Drawing from an unparalleled collection of interviews with early biotech players, Sally Smith Hughes offers the first book-length history of this pioneering company, depicting Genentech’s improbable creation, precarious youth, and ascent to immense prosperity. Hughes provides intimate portraits of the people significant to Genentech’s science and business, including cofounders Herbert Boyer and Robert Swanson, and in doing so sheds new light on how personality affects the growth of science. By placing Genentech’s founders, followers, opponents, victims, and beneficiaries in context, Hughes also demonstrates how science interacts with commercial and legal interests and university research, and with government regulation, venture capital, and commercial profits. Integrating the scientific, the corporate, the contextual, and the personal, Genentech tells the story of biotechnology as it is not often told, as a risky and improbable entrepreneurial venture that had to overcome a number of powerful forces working against it. 
Recently, the first "zoopharming" product has reached market approval: it is a recombinant human protein for medical use that is produced in the milk of transgenic goats. In addition, other transgenic animals, including faster-growing salmon and „environmentally friendly" pigs with reduced levels of phosphate in their faeces are awaiting regulatory approval. These are only some examples of upcoming applications of genetic engineering in farm animals. Other potential applications include traditional breeding goals such as higher milk or meat yields, leaner meat, and disease resistance. While genetic engineering in livestock opens a huge range of possibilities, it also brings about concerns of safety and justification: does genetic engineering affect animal welfare? Is it safe and morally acceptable to apply genetic engineering to farm animals for the various purposes that are envisaged?
It is against this background that the Europäische Akademie GmbH and the Berlin-Brandenburgische Akademie der Wissenschaften addressed the topic of transgenic farm animals in an interdisciplinary symposium in 2007. In these proceedings the following topics are covered: an analysis of the state of the art of the technology and its applications, an introduction to the specific application zoopharming (including its historical industrial development and the market for biopharmaceuticals), an assessment of ethical aspects, and considerations regarding the investigation of animal welfare implications of livestock biotechnology. The proceedings address science, industry, politics and the general public interested in the chances and risks of this upcoming field of biotechnology.
I turned to this book to get background on the biotech industry. A cursory review of the material showed me the topics were there. However, the book really needed editing for both clarity and style. Yes, the introduction may have been by a Nobel Laureate, but that doesn't mean it didn't need editing. Actually, there is the same introduction in all the books in the series.
Bioinformatics is an evolving field that is gaining popularity due to genomics, proteomics and other high-throughput biological methods. The function of bioinformatic scientists includes biological data storage, retrieval and in silico analysis of the results from large-scale experiments. This requires a grasp of knowledge mining algorithms, a thorough understanding of biological knowledge base, and the logical relationship of entities that describe a process or the system. Bioinformatics researchers are required to be trained in multidisciplinary fields of biology, mathematics and computer science. Currently the requirements are satisfied by ad hoc researchers who have specific skills in biology or mathematics/computer science. But the learning curve is steep and the time required to communicate using domain specific terms is becoming a major bottle neck in scientific productivity. This workbook provides hands-on experience which has been lacking for qualified bioinformatics researchers.
This edition covers all aspects of the subject needed by medical students. It is a volume in the Illustrated Colour Text series, with the subject matter divided into double-page spreads; this makes the information very accessible to the reader. Full use is made of flow charts and other graphics; clinical "boxes;" summary points; case histories; and clinical photographs. The whole orientation of the book is to concentrate on how clinical biochemistry relates to the care of the patient and to ensure that the medical student understands how to interpret laboratory.
Anton van Leeuwenhoek was not educated in science, but he created the best microscopes of the 17th century. He made more than 400 microscopes and used them to study living organisms. British scientist Robert Hooke was the first scientist to observe cells and give them their name.
Designed to supplement and complement any standard biochemistry text or lecture notes, this book helps provide a balanced picture of modern biochemistry by use of elementary mathematics in understanding properties and behavior of biological molecules. It provides a balanced picture of modern biochemistry by using elementary mathematics to explore the properties and behavior of biological molecules. The text discusses such topics as: Aqueous Solutions and Acid-Base Chemistry Chemistry of Biological Molecules Bioenergetics Enzymes Spectrophotometry and Other Optical Methods Isotopes in Biochemistry. Sample problems are solved completely in a step-by-step manner, and the answer to all practice problems are given at the end of the book. With Biochemical Calculations, 2nd Edition , students will gain confidence in their ability to handle mathematical problems, discovering that biochemistry is more than memorization of structures and pathways. Summary: Good bookRating: 5I received this book for the class. It helpful book for understanding and use typically rules for solve biochemical problems.Summary: The book is really goodRating: 5This book is definitely the best to read for anyone who deals with buffers biological systems protein purifications and so on. It reveals a lot of details so important for a practical chemist to know. The information inside of this book will definitely help you to save your time and money. It will in a very good and understandable way explain the most intricate questions. It can possibly change your vision of numerous key processes. One of the best advantages is that there is very little "water " in this book - you won't have to read 100 pages to get to the main idea. Really recommend to the chemistry majors. Summary: Theching Quantitative BiochemistryRating: 5As a biochemistry teacher, I find that a large number of our students are defficient in their quantitative skills. This is because many of them are biology majors, who do not have the best math background. This relatively inexpensive volume bridges the math gap for these students. It also provides the teacher with tools that increase his efficiency in dealing with the problem, without taking too much time away from the materials in the course syllabus. Although it is an older book, there is no modern replacement for what it does.Summary: Still Valuable After All These YearsRating: 5I have taught Biochemistry and Enzymology at the undergraduate and graduate level for over 20 years, and have recommended this book every year, to every student. Although the field of biochemistry has changed greatly during this time period, certain fundamental concepts have not changed at all, and remain central to a true understanding of how to do biochemistry. These include acid/base chemistry, energetics, enzyme kinetics, spectrophotometry, and isotopes. Of these, the first three gnerally give beginning (and even some advanced)students the most difficulty. In "Biochemical Calculations" Dr. Segel provides excellent explanations of the most important aspects of these topics.
A conceptual approach to clinical biochemistry, with humor. Includes a color map of Biochemistryland (an amusement park in which clinical biochemistry is seen as a whole, along with its key pathways, diseases, drugs, and laboratory tests). For biochemistry courses and medical Board review.
Unlike most Biotechnology textbooks, Dr. David P. Clark's "Biotechnology" approaches modern Biotechnology from a Molecular Basis, which grew out of the increasing biochemical understanding of physiology. Using straight forward, less-technical jargon, Clark manages to introduce each chapter with a basic concept, that ultimately evolves into a more specific detailed principle. This up-to-date text covers a wide realm of topics including forensics and bioethics using colorful illustrations and concise applications.
This concise, introductory text focuses on the basic principles of biochemistry, filling the gap between the encyclopedic volumes and the cursory overview texts.
Biotechnology is the major technology of the 21st century, yet few people realise how much it impacts on many aspects of human society. The defining aim of this new fifth edition is to re-establish the correct understanding of the term biotechnology. Using the straightforward style that made the previous editions of his textbook so popular, John Smith once again helps students with the deciphering and use of biological knowledge. He explains the historical developments in biotechnology and the range of activities from brewing beer, the treatment of sewage and other wastes, and the creation of biofuels. He also discusses the innovations in molecular biology, genomics and proteomics, systems biology and their impact on new biotechnology. In this edition John Smith also re-examines the ethics and morality of aspects of biotechnology and puts new emphasis on stem cells and regenerative medicine and micro RNA.
A conceptual approach to clinical biochemistry, with humor. Includes a color map of Biochemistryland
COMPREHENSIVE BIOTECHNOLOGY-I Cell Biology and Genetics. This book compre-hensively covers the syllabus of B.Sc (Biotechnology) I semester and clearly explains the basic concepts in Cell Biology and Genetics. A molecular approach to the study of cells is followed throughout the book.The text is illustrated by a large number of clearly drawn labelled diagrams for an easier understanding of the subject. Detailed cellular metabolism pathways are also mentioned wherever necessary for easy understanding.
Nuclear Structure And Gene Expression (CELL BIOLOGY: SERIES OF MONOGRAPHS)
Quantitative methods have a particular knack for improving any field they touch. For biology, computational techniques have led to enormous strides in our understanding of biological systems, but there is still vast territory to cover. Statistical physics especially holds great potential for elucidating the structural-functional relationships in biomolecules, as well as their static and dynamic properties. Breaking New Ground Computational Biology: A Statistical Mechanics Perspective is the first book dedicated to the interface between statistical physics and bioinformatics. Introducing both equilibrium and nonequilibrium statistical mechanics in a manner tailored to computational biologists, the author applies these methods to understand and model the properties of various biomolecules and biological networks at the systems level. Unique Vision, Novel Approach Blossey combines his enthusiasm for uniting the fields of physics and computational biology with his considerable experience, knowledge, and gift for teaching. He uses numerous examples and tasks to illustrate and test understanding of the concepts, and he supplies a detailed keyword list for easy navigation and comprehension. His approach takes full advantage of the latest tools in statistical physics and computer science to build a strong set of tools for confronting new challenges in computational biology. Making the concepts crystal clear without sacrificing mathematical rigor, Computational Biology: A Statistical Mechanics Perspective is the perfect tool to broaden your skills in computational biology.
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